Electroconductive and photocurrent generation properties of self-assembled monolayers formed by functionalized, conformationally-constrained peptides on gold electrodes

被引：31

作者：

Gatto, Emanuela ^{[1
,2
]}

Stella, Lorenzo ^{[1
,2
]}

Formaggio, Fernando ^{[3
]}

Toniolo, Claudio ^{[3
]}

Lorenzelli, Leandro ^{[4
]}

Venanzi, Mariano ^{[1
,2
]}

机构：

[1] Univ Roma Tor Vergata, Dept Chem Sci & Technol, I-00133 Rome, Italy

[2] Univ Roma Tor Vergata, Ctr NAST, I-00133 Rome, Italy

[3] Univ Padua, Dept Chem, Padova Unit, CNR,Inst Biomol Chem, I-35131 Padua, Italy

[4] IRST, Bruno Kessler Fdn, I-38050 Trento, Italy

来源：

JOURNAL OF PEPTIDE SCIENCE | 2008年 / 14卷 / 02期

关键词：

conformationally-constrained peptides; electroconductive properties; interdigitated gold microelectrodes; peptide self-assembled monolayers; photocurrent generation;

D O I：

10.1002/psc.973

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The electroconductive properties and photocurrent generation capabilities of self-assembled monolayers formed by conformationally-constrained hexapeptides were studied by cyclic voltammetry, chronoamperometry, and photocurrent generation experiments. Lipoic acid was covalently linked to the N-terminus of the peptides investigated to exploit the high affinity of the disulfide group to the gold substrates. Smart functionalization of the peptide scaffold with a redox-active (TOAC) or a photosensitizer (Trp) amino acid allowed us to study the efficiency of peptide-based self-assembled monolayers to mediate electron transfer and photoinduced electron transfer processes on gold substrates. Interdigitated microelectrodes have shown higher film stability under photoexcitation, lower dark currents, and higher sensitivity with respect to standard gold electrodes. Copyright (C) 2007 European Peptide Society and John Wiley & Sons, Ltd.

引用

页码：184 / 191

页数：8

共 40 条

[1] Single-wall carbon nanotube films for photocurrent generation. A prompt response to visible-light irradiation [J].