The Obesity Paradox

被引:140
作者
Amundson, Dennis E. [1 ]
Djurkovic, Svetolik [2 ]
Matwiyoff, Gregory N.
机构
[1] USN, Dept Pulm Crit Care Med, San Diego Med Ctr, San Diego, CA 92152 USA
[2] Inova Hlth Syst Crit Care Med, Dept Med, Falls Church, VA 22042 USA
关键词
Obesity; Obesity paradox; Consequences of obesity; BODY-MASS INDEX; PERCUTANEOUS CORONARY INTERVENTION; PERITONEAL-DIALYSIS PATIENTS; RENAL-DISEASE PATIENTS; SHORT-TERM SURVIVAL; HEMODIALYSIS-PATIENTS; MYOCARDIAL-INFARCTION; HEART-FAILURE; CLINICAL-OUTCOMES; ARTERY-DISEASE;
D O I
10.1016/j.ccc.2010.06.004
中图分类号
R4 [临床医学];
学科分类号
100218 [急诊医学];
摘要
The term obesity paradox' refers to the observation that although obesity is a major risk factor in the development of cardiovascular and peripheral vascular disease when acute cardiovascular decompensation occurs for example in myocardial infarction or congestive heart failure obese patients may have a survival benefit In addition it has been suggested that obese patients tend to fare better after certain surgical procedures such as coronary artery bypass surgery Moreover it appears that obese men with chronic hypertensive heart disease live longer than men of normal weight Mounting evidence shows that obesity alone may confer a survival benefit independent of age medical care or therapy Perhaps the definition of obesity needs to be revisited and it is also possible that all fat is not equal
引用
收藏
页码:583 / 596
页数:14
相关论文
共 64 条
[1]
Body mass index, dialysis modality, and survival: Analysis of the United States Renal Data System Dialysis Morbidity and Mortality Wave II Study [J].
Abbott, KC ;
Glanton, CW ;
Trespalacios, FC ;
Oliver, DK ;
Ortiz, MI ;
Agodoa, LY ;
Cruess, DF ;
Kimmel, PL .
KIDNEY INTERNATIONAL, 2004, 65 (02) :597-605
[2]
Assessment and management of the obese patient [J].
Abir, F ;
Bell, R .
CRITICAL CARE MEDICINE, 2004, 32 (04) :S87-S91
[3]
Obesity and mortality from cancer [J].
Adami, HO ;
Trichopoulos, D .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (17) :1623-1624
[4]
Effect of obesity on intensive care morbidity and mortality: A meta-analysis [J].
Akinnusi, Morohunfolu E. ;
Pineda, Lilibeth A. ;
El Solh, Ali A. .
CRITICAL CARE MEDICINE, 2008, 36 (01) :151-158
[5]
Arena R, 2010, FUTUR CARDIOL, V6, P1, DOI [10.2217/fca.09.158, 10.2217/FCA.09.158]
[6]
Aslam N, 2002, PERITON DIALYSIS INT, V22, P191
[7]
Obesity-related excess mortality rate in an adult intensive care unit: A risk-adjusted matched cohort study [J].
Bercault, N ;
Boulain, T ;
Kuteifan, K ;
Wolf, M ;
Runge, I ;
Fleury, JC .
CRITICAL CARE MEDICINE, 2004, 32 (04) :998-1003
[8]
BORSTEIN S, 1998, J CLIN ENDOCRINAL ME, V83, P280
[9]
Body-mass index and mortality in a prospective cohort of US adults [J].
Calle, EE ;
Thun, MJ ;
Petrelli, JM ;
Rodriguez, C ;
Heath, CW .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (15) :1097-1105
[10]
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults [J].
Calle, EE ;
Rodriguez, C ;
Walker-Thurmond, K ;
Thun, MJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (17) :1625-1638