Synthesis of the C(1)-C(25) fragment of amphidinol 3: Application of the double-allylboration reaction for synthesis of 1,5-diols

被引：68

作者：

Flamme, EM ^{[1
]}

Roush, WR ^{[1
]}

机构：

[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 07期

关键词：

D O I：

10.1021/ol050250q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthesis of the C(1)-C(25) fragment of amphidinol 3 is described. The synthesis features two applications of double allylboration reaction methodology for the highly stereoselective synthesis of 1,5-diol units in the C(l)-C(15) segment.

引用

页码：1411 / 1414

页数：4

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