In vitro and in vivo interactions between the hepatitis B virus protein P22 and the cellular protein gC1qR

被引：27

作者：

Lainé, S

Thouard, A

Derancourt, J

Kress, A

Sitterlin, D

Rossignol, JM ^{[1
]}

机构：

[1] Univ Versailles, Lab Genet & Biol Cellulaire, F-78000 Versailles, France

[2] CNRS, Ctr Rech Biochim Macromol, Montpellier, France

[3] Inst Andre Lwoff, Villejuif, France

来源：

JOURNAL OF VIROLOGY | 2003年 / 77卷 / 23期

关键词：

D O I：

10.1128/JVI.77.23.12875-12880.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

gC1qR, a mitochondrial matrix protein, was identified as the main cellular partner of the hepatitis B virus P22 protein. We demonstrated by immunofluorescence studies that some P22 molecules were colocalized with the endogenous gC1qR in both the cytoplasm and the nucleus but never in the mitochondria. We also showed that the last 34 amino acids of P22 were involved in the association with gC1qR.

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页码：12875 / 12880

页数：6

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