Intracellular applications of analytical SERS spectroscopy and multispectral imaging

被引：95

作者：

Chourpa, Igor ^{[2
,3
]}

Lei, Franck H. ^{[1
]}

Dubois, Pierre ^{[2
,3
]}

Manfait, Michel ^{[1
]}

Sockalingum, Ganesh D. ^{[1
]}

机构：

[1] Univ Reims, MeDIAN, CNRS, UMR 6237,MEDyC,UFR Pharm, F-51096 Reims, France

[2] Univ Tours, Fac Pharm, F-37200 Tours, France

[3] Inst Fed Rech Imagerie Fonct 135, F-37000 Tours, France

来源：

CHEMICAL SOCIETY REVIEWS | 2008年 / 37卷 / 05期

关键词：

D O I：

10.1039/b714732p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The aim of this tutorial review is to give an overview of the state of the art of intracellular applications of analytical SERS spectroscopy. We pay particular attention to nanoparticle-based SERS spectroscopy since this currently dominates the published literature on non-disturbing analysis of live cells. We describe recent advances in this domain due to the development of multispectral imaging and to the combined use of SERRS (surface-enhanced resonance Raman scattering) and fluorescence spectroscopy. Finally, a perspective view is given on the tip-based approaches like tip-enhanced Raman spectroscopy (TERS) which allow micrometric and nanometric resolution.

引用

页码：993 / 1000

页数：8

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