Hydrogenation and hydrogenolysis with Pd/C in poly(ethylene glycol) (PEG): A practical and recyclable medium

被引:21
作者
Chandrasekhar, S [1 ]
Shyamsunder, T [1 ]
Chandrashekar, G [1 ]
Narsihmulu, C [1 ]
机构
[1] Indian Inst Chem Technol, Div Organ Chem 1, Hyderabad 500007, Andhra Pradesh, India
关键词
hydrogenation; hydrogenolysis; Pd/C; poly (ethylene glycol); recycling;
D O I
10.1055/s-2003-45007
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Pd/C in PEG (400) has been found to be an efficient reusable reaction medium for hydrogenation and hydrogenolysis. Both the catalyst and PEG were recycled efficiently over four runs without appreciable loss of activity.
引用
收藏
页码:522 / 524
页数:3
相关论文
共 30 条
[1]  
[Anonymous], 1996, REDUCTIONS ORGANIC C
[2]   ENZYMATIC PEPTIDE SYNTHESES IN ORGANIC-SOLVENT MEDIATED BY MODIFIED ALPHA-CHYMOTRYPSIN [J].
BABONNEAU, MT ;
JACQUIER, R ;
LAZARO, R ;
VIALLEFONT, P .
TETRAHEDRON LETTERS, 1989, 30 (21) :2787-2790
[3]  
BADONE D, 1987, SYNTHESIS-STUTTGART, P920
[4]   PREPARATION OF A CHIRAL LACTONE FROM LAEVOGLUCOSAN - A KEY INTERMEDIATE FOR SYNTHESIS OF THE SPIROACETAL MOIETIES OF THE AVERMECTINS AND MILBEMYCINS [J].
BAKER, R ;
BOYES, RHO ;
BROOM, DMP ;
OMAHONY, MJ ;
SWAIN, CJ .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1987, (07) :1613-1621
[5]   Supported palladium catalysts for fine chemicals synthesis [J].
Blaser, HU ;
Indolese, A ;
Schnyder, A ;
Steiner, H ;
Studer, M .
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2001, 173 (1-2) :3-18
[6]   A chemically inert hydrophilic resin for solid phase organic synthesis. [J].
Buchardt, J ;
Meldal, M .
TETRAHEDRON LETTERS, 1998, 39 (47) :8695-8698
[7]   Poly(ethylene glycol) (PEG) as a reusable solvent medium for organic synthesis. Application in the Heck reaction [J].
Chandrasekhar, S ;
Narsihmulu, C ;
Sultana, SS ;
Reddy, NR .
ORGANIC LETTERS, 2002, 4 (25) :4399-4401
[8]   Osmium tetroxide in poly(ethylene glycol) (PEG): a recyclable reaction medium for rapid asymmetric dihydroxylation under Sharpless conditions [J].
Chandrasekhar, S ;
Narsihmulu, C ;
Sultana, SS ;
Reddy, NR .
CHEMICAL COMMUNICATIONS, 2003, (14) :1716-1717
[9]   PALLADIUM-CATALYZED REDUCTIONS OF ALPHA, BETA-UNSATURATED CARBONYL-COMPOUNDS, CONJUGATED DIENES, AND ACETYLENES WITH TRIALKYLAMMONIUM FORMATES [J].
CORTESE, NA ;
HECK, RF .
JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (20) :3985-3987
[10]   Influence of organic solvents on enzyme chemoselectivity and their role in enzyme-substrate interaction [J].
Ebert, C ;
Gardossi, L ;
Linda, P ;
Vesnaver, R ;
Bosco, M .
TETRAHEDRON, 1996, 52 (13) :4867-4876