Implicit solvent simulation models for biomembranes

被引：120

作者：

Brannigan, G

Lin, LCL

Brown, FLH ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

[2] Univ Calif Santa Barbara, Dept Phys & Astron, Santa Barbara, CA 93106 USA

来源：

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS | 2006年 / 35卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1007/s00249-005-0013-y

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Fully atomic simulation strategies are infeasible for the study of many processes of interest to membrane biology, biophysics and biochemistry. We review various coarse-grained simulation methodologies with special emphasis on methods and models that do not require the explicit simulation of water. Examples from our own research demonstrate that such models have potential for simulating a variety of biologically relevant phenomena at the membrane surface.

引用

收藏

页码：104 / 124

页数：21

相关论文

共 201 条

[1] SIMULATIONS USING HARD PARTICLES [J].

ALLEN, MP .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 1993, 344 (1672) :323-337

[2]

[Anonymous], BIOL MEMBRANES

[3] CONSTANT-PRESSURE MOLECULAR-DYNAMICS SIMULATIONS OF THE CRYSTAL-SMECTIC TRANSITION IN SYSTEMS OF SOFT PARALLEL SPHEROCYLINDERS [J].

AOKI, KM ;

YONEZAWA, F .

PHYSICAL REVIEW A, 1992, 46 (10) :6541-6549

[4] Interaction between inclusions embedded in membranes [J].

ArandaEspinoza, H ;

Berman, A ;

Dan, N ;

Pincus, P ;

Safran, S .

BIOPHYSICAL JOURNAL, 1996, 71 (02) :648-656

[5] Bridging microscopic and mesoscopic simulations of lipid bilayers [J].

Ayton, G ;

Voth, GA .

BIOPHYSICAL JOURNAL, 2002, 83 (06) :3357-3370

[6] Interfacing continuum and molecular dynamics: An application to lipid bilayers [J].

Ayton, G ;

Bardenhagen, SG ;

McMurtry, P ;

Sulsky, D ;

Voth, GA .

JOURNAL OF CHEMICAL PHYSICS, 2001, 114 (15) :6913-6924

[7] LOCAL UNBINDING OF PINCHED MEMBRANES [J].

BARZIV, R ;

MENES, R ;

MOSES, E ;

SAFRAN, SA .

PHYSICAL REVIEW LETTERS, 1995, 75 (18) :3356-3359

[8]

BENSHAUL A, 1995, STRUCTURE DYNAMICS M, V1

[9] PHYSICAL-PROPERTIES OF THE FLUID LIPID-BILAYER COMPONENT OF CELL-MEMBRANES - A PERSPECTIVE [J].

BLOOM, M ;

EVANS, E ;

MOURITSEN, OG .

QUARTERLY REVIEWS OF BIOPHYSICS, 1991, 24 (03) :293-397

[10] How chain length, headgroup polymerization, and anomeric configuration govern the thermotropic and lyotropic liquid crystalline phase behavior and the air-water interfacial adsorption of glucose-based surfactants [J].

Boyd, BJ ;

Drummond, CJ ;

Krodkiewska, I ;

Grieser, F .

LANGMUIR, 2000, 16 (19) :7359-7367

← 1 2 3 4 5 6 7 8 9 10 →