Synthesis and self-assembly of rod-rod hybrid poly(γ-benzyl L-glutamate)-block-polyisocyanide copolymers

被引：64

作者：

Kros, A

Jesse, W

Metselaar, GA

Cornelissen, JJLM

机构：

[1] Leiden Univ, Leiden Inst Chem, Dept Soft Matter Chem, NL-2300 RA Leiden, Netherlands

[2] Radboud Univ Nijmegen, Inst Mol & Mat, Dept Organ Chem, NL-6525 ED Nijmegen, Netherlands

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 28期

关键词：

block copolymers; peptides; self-assembly; vesicles;

D O I：

10.1002/anie.200500877

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Connecting rods: Rigid rod-rod block copolymers are synthesized from peptide and polyisocyanide blocks (see picture: blue = poly(γ-benzyl L-glutamate); red = poly(methylbenzyl isocyanide) or poly-(L-isocyanoalanyl-L-alanine methyl ester). The polyisocyanide helix has side arms organized in a parallel β-sheet (light blue). Some copolymers self-assemble into ordered layers of hollow capsules. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4349 / 4352

页数：4

共 23 条

[1] Stimuli-responsive polypeptide vesicles by conformation-specific assembly [J].