Two strategies to increase adherence to HIV antiretroviral medication: Life-steps and medication monitoring

被引:236
作者
Safren, SA
Otto, MW
Worth, JL
Salomon, E
Johnson, W
Mayer, K
Boswell, S
机构
[1] Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
[3] Fenway Community Hlth, Boston, MA USA
关键词
adherence; compliance; HIV; AIDS; antiretroviral therapy;
D O I
10.1016/S0005-7967(00)00091-7
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Advances in the medical treatment of HIV have made it clear that adherence to highly active antiretroviral treatment is a crucial feature for treatment success. The present paper had two goals: (1) to examine psychosocial predictors of adherence in persons receiving HIV antiretroviral therapy; (2) to compared two minimal-treatment interventions to increase HIV medication adherence in a subset of persons who self-reported less than perfect adherence. One of the interventions, Life-Steps, is a single-session intervention utilizing cognitive-behavioral, motivational interviewing, and problem-solving techniques. The other intervention, self-monitoring, utilizes a pill-diary and an adherence questionnaire alone. Significant correlates of adherence included depression, social support, adherence self-efficacy, and punishment beliefs about HIV. Depression was a significant unique predictor of adherence over and above the other variables. Both interventions yielded improvement in adherence from baseline, and the Life-Steps intervention showed faster improvements in adherence for persons with extant adherence problems. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1151 / 1162
页数:12
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