Base effect on the palladium catalyzed α-arylation of N-benzyl-2-piperidinones

被引：20

作者：

Cossy, J ^{[1
]}

de Filippis, A ^{[1
]}

Pardo, DG ^{[1
]}

机构：

[1] ESPCI, CNRS, Lab Chim Organ Associe, F-75231 Paris 05, France

来源：

SYNLETT | 2003年 / 14期

关键词：

arylations; lactams; palladium; zinc; coupling;

D O I：

10.1055/s-2003-42081

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A very simple method for obtaining alpha-arylated N-benzyl-2-piperidinones in high yields is described. The use of s-BuLi as the base and Pd(dba)(2) as the catalyst are the key factors.

引用

页码：2171 / 2174

页数：4

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