Optimizing Platelet Inhibition in Clopidogrel Poor Metabolizers Therapeutic Options and Practical Considerations

被引：21

作者：

Angiolillo, Dominick J. ^{[1
]}

Ueno, Masafumi ^{[1
]}

机构：

[1] Univ Florida, Coll Med Jacksonville, Dept Med, Div Cardiol, Jacksonville, FL 32209 USA

来源：

JACC-CARDIOVASCULAR INTERVENTIONS | 2011年 / 4卷 / 04期

关键词：

antiplatelet therapy; genetics; platelet reactivity; MAINTENANCE-DOSE CLOPIDOGREL; CORONARY-ARTERY-DISEASE; ADJUNCTIVE CILOSTAZOL; ANTIPLATELET THERAPY; DIABETES-MELLITUS; CYP2C19; GENOTYPE; VARIABILITY; REACTIVITY; PRASUGREL; CONSENSUS;

D O I：

10.1016/j.jcin.2011.03.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：411 / 414

页数：4

共 25 条

[1] Prasugrel Overcomes High On-Clopidogrel Platelet Reactivity Post-Stenting More Effectively Than High-Dose (150-mg) Clopidogrel The Importance of CYP2C19*2 Genotyping [J].

Alexopoulos, Dimitrios ;

Dimitropoulos, Gerasimos ;

Davlouros, Periklis ;

Xanthopoulou, Ioanna ;

Kassimis, George ;

Stavrou, Eleana F. ;

Hahalis, George ;

Athanassiadou, Aglaia .

JACC-CARDIOVASCULAR INTERVENTIONS, 2011, 4 (04) :403-410

[2]

ANGIOLILLO DJ, 2011, J AM COLL C IN PRESS

[3] A randomized study assessing the impact of cilostazol on platelet function profiles in patients with diabetes mellitus and coronary artery disease on dual antiplatelet therapy: results of the OPTIMUS-2 study [J].

Angiolillo, Dominick J. ;

Capranzano, Piera ;

Goto, Shinya ;

Aslam, Mohammed ;

Desai, Bhaloo ;

Charlton, Ronald K. ;

Suzuki, Yoshie ;

Box, Lyndon C. ;

Shoemaker, Steven B. ;

Zenni, Martin M. ;

Guzman, Luis A. ;

Bass, Theodore A. .

EUROPEAN HEART JOURNAL, 2008, 29 (18) :2202-2211

[4] Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease - Results of the Optimizing antiPlatelet Therapy In diabetes MellitUS (OPTIMUS) study [J].

Angiolillo, Dominick J. ;

Shoemaker, Steven B. ;

Desai, Bhaloo ;

Yuan, Hang ;

Charlton, Ronald K. ;

Bernardo, Esther ;

Zenni, Martin M. ;

Guzman, Luis A. ;

Bass, Theodore A. ;

Costa, Marco A. .

CIRCULATION, 2007, 115 (06) :708-716

[5] Variability in individual responsiveness to clopidogrel - Clinical implications, management, and future perspectives [J].

Angiolillo, Dominick J. ;

Fernandez-Ortiz, Antonio ;

Bernardo, Esther ;

Alfonso, Fernando ;

Macaya, Carlos ;

Bass, Theodore A. ;

Costa, Marco A. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 49 (14) :1505-1516

[6] Increased Platelet Inhibition After Switching From Maintenance Clopidogrel to Prasugrel in Patients With Acute Coronary Syndromes Results of the SWAP (SWitching Anti Platelet) Study [J].

Angiolillo, Dominick J. ;

Saucedo, Jorge F. ;

DeRaad, Roger ;

Frelinger, Andrew L. ;

Gurbel, Paul A. ;

Costigan, Timothy M. ;

Jakubowski, Joseph A. ;

Ojeh, Clement K. ;

Effron, Mark B. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2010, 56 (13) :1017-1023

[7] No Role for Triple Antiplatelet Therapy? [J].

Antoniucci, David .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 57 (03) :290-291

[8] Pilot Study of the Antiplatelet Effect of Increased Clopidogrel Maintenance Dosing and Its Relationship to CYP2C19 Genotype in Patients With High On-Treatment Reactivity [J].

Barker, Colin M. ;

Murray, Sarah S. ;

Teirstein, Paul S. ;

Kandzari, David E. ;

Topol, Eric J. ;

Price, Matthew J. .

JACC-CARDIOVASCULAR INTERVENTIONS, 2010, 3 (10) :1001-1007

[9] Clopidogrel-Drug Interactions [J].

Bates, Eric R. ;

Lau, Wei C. ;

Angiolillo, Dominick J. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 57 (11) :1251-1263

[10] Consensus and Future Directions on the Definition of High On-Treatment Platelet Reactivity to Adenosine Diphosphate [J].

Bonello, Laurent ;

Tantry, Udaya S. ;

Marcucci, Rossella ;

Blindt, Ruediger ;

Angiolillo, Dominick J. ;

Becker, Richard ;

Bhatt, Deepak L. ;

Cattaneo, Marco ;

Collet, Jean Philippe ;

Cuisset, Thomas ;

Gachet, Christian ;

Montalescot, Gilles ;

Jennings, Lisa K. ;

Kereiakes, Dean ;

Sibbing, Dirk ;

Trenk, Dietmar ;

Van Werkum, Jochem W. ;

Paganelli, Franck ;

Price, Matthew J. ;

Waksman, Ron ;

Gurbel, Paul A. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2010, 56 (12) :919-933

← 1 2 3 →