Effect of protease inhibitors combined with standard antiretroviral therapy on linear growth and weight gain in human immunodeficiency virus type 1-infected children

被引：24

作者：

Dreimane, D

Nielsen, K

Deveikis, A

Bryson, YJ

Geffner, ME

机构：

[1] Univ Calif Los Angeles, Mattel Childrens Hosp, Dept Pediat, Los Angeles, CA USA

[2] Mem Miller Childrens Hosp, Long Beach, CA USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2001年 / 20卷 / 03期

关键词：

human immunodeficiency virus type 1 infection in children; protease inhibitors; linear growth; weight gain;

D O I：

10.1097/00006454-200103000-00020

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Children with HIV-1 infection and poor growth have a significant increase in the risk of death. We studied the effects of protease inhibitors on the height and weight of 27 HIV-1-infected children and found that in our small pilot study, protease inhibitor therapy had a positive effect on the heights of HIV-1-infected children. Accelerated height velocity was sustained for at least 18 to 20 months.

引用

收藏

页码：315 / 316

页数：2

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