Molecular phylogeny of modern coxsackievirus A16

被引:139
作者
Perera, D.
Yusof, M. A.
Podin, Y.
Ooi, M. H.
Thao, N. T. T.
Wong, K. K.
Zaki, A.
Chua, K. B.
Malik, Y. A.
Tu, P. V.
Tien, N. T. K.
Puthavathana, P.
McMinn, P. C.
Cardosa, M. J. [1 ]
机构
[1] Univ Malaysia Sarawak, Inst Hlth & Commun Med, Kota Samarahan 94300, Sarawak, Malaysia
[2] Inst Med Res, Kuala Lumpur, Malaysia
[3] Sibu Hosp, Sarawak, Malaysia
[4] Inst Pasteur, Ho Chi Minh City, Vietnam
[5] Univ Kebangsaan Malaysia, Fac Med, Bangi, Malaysia
[6] Dr Fakeeh Hosp, Jeddah, Saudi Arabia
[7] Natl Publ Hlth Lab, Sungai Buloh, Selangor, Malaysia
[8] Int Med Univ, Kuala Lumpur, Malaysia
[9] Mahidol Univ, Fac Med, Siriraj Hosp, Bangkok 10700, Thailand
[10] Telethon Inst Child Hlth Res, Perth, WA, Australia
基金
英国惠康基金;
关键词
D O I
10.1007/s00705-006-0934-5
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A phylogenetic analysis of VP1 and VP4 nucleotide sequences of 52 recent CVA16 strains demonstrated two distinct CVA16 genogroups, A and B, with the prototype strain being the only member of genogroup A. CVA16 G-10, the prototype strain, showed a nucleotide difference of 27.7-30.2% and 19.9-25.2% in VP1 and VP4, respectively, in relation to other CVA16 strains, which formed two separate lineages in genogroup B with nucleotide variation of less than 13.4% and less than 16.3% in VP1 and VP4, respectively. Lineage 1 strains circulating before 2000 were later displaced by lineage 2 strains.
引用
收藏
页码:1201 / 1208
页数:8
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