Highly stereoselective formation of Cp*IrCl complexes of N,N-dimethylamino acids

被引：40

作者：

Grotjahn, DB ^{[1
]}

Joubran, C ^{[1
]}

Hubbard, JL ^{[1
]}

机构：

[1] UTAH STATE UNIV,DEPT CHEM & BIOCHEM,LOGAN,UT 84322

来源：

ORGANOMETALLICS | 1996年 / 15卷 / 04期

关键词：

D O I：

10.1021/om9507890

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

N,N-Dimethylamino acids serve as (N, O)-chelating monoanionic ligands to the prochiral fragment Cp*IrCl. A series of four such complexes and one Rh analog all were formed with diastereoselectivity of greater than or equal to 50: less than or equal to 1. The structure of the valine complex 5d (C17H29ClIrNO2) was analyzed at 298 K, from which a cis-arrangement of Cp* and valine side chain (i-Pr) was revealed. Solution NMR studies of 5d, aided by an unusual zero coupling between the two methine protons of the amino acid, showed that the structures in solution and the solid were very similar. The preference for the cis-oriented Cp* and amino acid side chain in 5 is attributed to a maximum number of gauche interactions in the metallacycle and its substituents, especially pronounced for N,N-disubstituted amino acids.

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页码：1230 / 1235

页数：6

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