Ethanol consumption in rats selectively bred for differential saccharin intake

被引：78

作者：

Dess, NK

Badia-Elder, NE

Thiele, TE

Kiefer, SW

Blizard, DA

机构：

[1] Occidental Coll, Dept Psychol, Los Angeles, CA 90041 USA

[2] Kansas State Univ, Dept Psychol, Manhattan, KS 66506 USA

[3] Penn State Univ, Ctr Dev & Hlth Genet, University Pk, PA 16802 USA

来源：

ALCOHOL | 1998年 / 16卷 / 04期

关键词：

ethanol consumption; reciprocal selection; selective breeding;

D O I：

10.1016/S0741-8329(98)00010-X

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Rat lines selectively bred for high ethanol consumption consume more saccharin solution than do their low-ethanol-consuming counterparts. The present study utilized the technique of reciprocal selection to examine the reliability of the saccharin/ethanol relationship; specifically, consumption of 1-10% ethanol solution was measured in rats selectively bred for high vs, low saccharin consumption (Occidental HiS and LoS lines). HiS rats consumed more ethanol than did LoS rats. These results support the idea that individual differences in ethanol and saccharin consumption share some common mechanism(s). (C) 1998 Elsevier Science Inc.

引用

页码：275 / 278

页数：4

共 28 条

[1] ETHANOL PREFERENCE IN THE HARRINGTON DERIVATION OF THE MAUDSLEY REACTIVE AND NONREACTIVE STRAINS [J].