End-to-end self-assembly and colorimetric characterization of gold nanorods and nanospheres via oligonucleotide hybridization

被引：75

作者：

Pan, BF ^{[1
]}

Ao, LM ^{[1
]}

Gao, F ^{[1
]}

Tian, HY ^{[1
]}

He, R ^{[1
]}

Cui, DX ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Dept Bionanosci & Engn, Natl Key Lab Nano Micro Fabricat Technol, Inst Micronanosci & Technol, Shanghai 200030, Peoples R China

来源：

NANOTECHNOLOGY | 2005年 / 16卷 / 09期

关键词：

D O I：

10.1088/0957-4484/16/9/061

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

We report end-to-end assembly for tuning the optical properties of a gold nanorod/sphere based on oligonucleotide hybridization. The rationale behind the selection of the mercaptoalkyloligonucleotide molecule is based on the fact that the thiol group binds to the ends of the nanorods, which further assemble in an end-to-end fashion through hybridization with the target oligonucleotide. A highly selective, colorimetric polynucleotide detection method based on mercaptoalkyloligonucleotide-modified gold nanorod/sphere probes is also reported.

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收藏

页码：1776 / 1780

页数：5

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