Structurally simple, modular amino alcohols for the recognition of carboxylic acids.: Application to the development of a new chiral solvating agent

被引：65

作者：

Cuevas, F

Ballester, P

Pericàs, MA

机构：

[1] Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain

[2] Univ Barcelona, Dept Quim Organ, Barcelona 08008, Spain

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 24期

关键词：

D O I：

10.1021/ol052490b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two flexible receptors for carboxylic acids, based on 1-amino-3-fluoro-2-alcohol functional arrays and built on aminomethylpyridine platforms, are described. The C(2)-symmetric one [from 2,6-bis(aminomethyl)pyridine] has been shown to be an efficient CSA due to its ability to form geometrically different diastereomeric complexes enabling the discrimination between the enantiomers of a series of carboxylic acid in the (1)H NMR spectra.

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页码：5485 / 5487

页数：3

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