Tinea capitis: Fluconazole in Trichophyton tonsurans infection

被引:16
作者
Mercurio, MG [1 ]
Silverman, RA [1 ]
Elewski, BE [1 ]
机构
[1] Univ Rochester, Sch Med & Dent, Rochester, NY USA
关键词
D O I
10.1046/j.1525-1470.1998.1998015229.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Tinea capitis is the most common dermatophyte infection in children, Trichophyton tonsurans is the most common etiologic agent in the United States, and for more than four decades the standard therapy has been griseofulvin, The availability of newer, and often more effective, antifungal drugs creates the opportunity for choice and the ability to optimally tailor treatment for a particular patient, Fluconazole is an azole antifungal drug available in a pleasant, well-tolerated, liquid formulation ideal for the pediatric population. It has a good safety profile and is approved in the United States for use in children, although not for tinea capitis, We present five patients with tinea capitis successfully treated with fluconazole.
引用
收藏
页码:229 / 232
页数:4
相关论文
共 22 条
[1]   ADVERSE DRUG-INTERACTIONS CLINICALLY IMPORTANT FOR THE DERMATOLOGIST [J].
ANDERSEN, WK ;
FEINGOLD, DS .
ARCHIVES OF DERMATOLOGY, 1995, 131 (04) :468-473
[2]   FLUCONAZOLE PENETRATION INTO CEREBROSPINAL-FLUID - IMPLICATIONS FOR TREATING FUNGAL-INFECTIONS OF THE CENTRAL NERVOUS-SYSTEM [J].
ARNDT, CAS ;
WALSH, TJ ;
MCCULLY, CL ;
BALIS, FM ;
PIZZO, PA ;
POPLACK, DG .
JOURNAL OF INFECTIOUS DISEASES, 1988, 157 (01) :178-180
[3]   CLINICAL PEARL - SYSTEMIC ANTIFUNGAL DRUGS AND DRUG-INTERACTIONS [J].
BRODELL, RT ;
ELEWSKI, BE .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1995, 33 (02) :259-260
[4]   Tinea capitis [J].
Elewski, B .
DERMATOLOGIC CLINICS, 1996, 14 (01) :23-+
[5]   TINEA-CAPITIS - ITRACONAZOLE IN TRICHOPHYTON-TONSURANS INFECTION [J].
ELEWSKI, BE .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1994, 31 (01) :65-67
[6]  
GALGIANI JN, 1990, ANN INTERN MED, V1113, P899
[7]   EPIDEMIOLOGY AND TREATMENT OF TINEA-CAPITIS - KETOCONAZOLE VS GRISEOFULVIN [J].
GAN, VN ;
PETRUSKA, M ;
GINSBURG, CM .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1987, 6 (01) :46-49
[8]   TREATMENT OF KERION WITH FLUCONAZOLE [J].
GATTI, S ;
MARINARO, C ;
BIANCHI, L ;
NINI, G .
LANCET, 1991, 338 (8775) :1156-1156
[9]   FLUCONAZOLE - AN UPDATE OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES AND THERAPEUTIC USE IN MAJOR SUPERFICIAL AND SYSTEMIC MYCOSES IN IMMUNOCOMPROMISED PATIENTS [J].
GOA, KL ;
BARRADELL, LB .
DRUGS, 1995, 50 (04) :658-690
[10]   Treatment of tinea capitis with itraconazole [J].
Greer, DL .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1996, 35 (04) :637-638