Identification of isopseudohypericin, a new phenanthroperylene quinone obtained by the alkaline treatment of pseudohypericin

被引：6

作者：

Fourneron, JD ^{[1
]}

Naït-Si, Y

Rosas, R

Faure, R

Viant, P

机构：

[1] Fac Sci & Tech St Jerome, Lab Syst Chim Complexes, CNRS, UMR 6171, F-13397 Marseille 20, France

[2] Fac Sci & Tech St Jerome, Ctr Reg RMN, F-13397 Marseille 20, France

[3] RD Pharma SA, F-98000 Monaco, Monaco

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 33期

关键词：

Hypericum perforatum; pseudohypericin; isopseudohypericin; new phenanthroperylene quinone;

D O I：

10.1016/S0040-4039(03)01527-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

At high pH, pseudohypericin from St. John's Wort (Hypericum perforatum) is converted into a single product which has been isolated. LC-MS analysis indicated that the molar mass of this product is identical to that of pseudohypericin. H-1 and C-13 NMR analysis indicated that the compound is a novel phenanthroperylene quinone which we have named isopseudohypericin; it is a cyclic ether which is an isomer of pseudohypericin. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：6285 / 6288

页数：4

共 17 条

[1]

Altmann R, 1997, MONATSH CHEM, V128, P571, DOI 10.1007/BF00807587

[2] St John's wort (Hypericum perforatum L.):: a review of its chemistry, pharmacology and clinical properties [J].