Antibacterial activity of Leontopodium alpinum (Edelweiss)

被引：38

作者：

Dobner, MJ

Schwaiger, S

Jenewein, IH

Stuppner, H ^{[1
]}

机构：

[1] Leopold Franzens Univ Innsbruck, Inst Pharm, Abt Pharmakognosie, A-6020 Innsbruck, Austria

[2] Leopold Franzens Univ Innsbruck, Inst Hyg, A-6020 Innsbruck, Austria

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2003年 / 89卷 / 2-3期

基金：

奥地利科学基金会;

关键词：

Leontopodium; Ethnomedicine; antibacterial; bisabolanes; sesquiterpenes;

D O I：

10.1016/j.jep.2003.09.004

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Extracts and individual constituents of Leontopodium alpinum Cass. (Asteraceae) were tested for their antimicrobial activity in two different assays. Extracts were screened in agar diffusion assays, whereas the minimum inhibitory concentrations (MIC) of single compounds were determined by the microbroth dilution method according to NCCLS criteria. Significant, antimicrobial activities were found against various strains of Enterococcus faecium, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes strains. These results support the ethnomedicinal use of Leontopodium alpinum for the treatment of respiratory and abdominal disorders. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

引用

页码：301 / 303

页数：3

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