Differential skeletal muscle expression of myostatin across teleost species, and the isolation of multiple myostatin isoforms

被引：187

作者：

Roberts, SB ^{[1
]}

Goetz, FW ^{[1
]}

机构：

[1] Univ Notre Dame, Dept Biol Sci, Notre Dame, IN 46556 USA

来源：

FEBS LETTERS | 2001年 / 491卷 / 03期

基金：

美国海洋和大气管理局;

关键词：

myostatin; trout; muscle; ovulation; ovary;

D O I：

10.1016/S0014-5793(01)02196-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Two myostatin (MSTN) isoforms were isolated from brook trout with 92% identity in corresponding regions at the nucleotide level. One isoform was isolated from muscle and brain and the second from ovarian tissue. To our knowledge this is the first time two MSTN isoforms have been isolated from a given vertebrate species. Within the brain, MSTN transcripts were localized to the optic lobes, hindbrain, and hypothalamus. In the trout ovary, MSTN transcripts were upregulated at ovulation in several females. MSTN cDNA fragments were also isolated from several other fish species and differential expression of MSTN among muscle fiber types was observed. (C) 2001 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：212 / 216

页数：5

共 23 条

[1]

Expression of a novel member of the TGF-β superfamily, growth differentiation factor-15/macrophage-inhibiting cytokine-1 (GDF-15/MIC-1) in adult rat tissues [J].

Böttner, M ;

Suter-Crazzolara, C ;

Schober, A ;

Unsicker, K .

CELL AND TISSUE RESEARCH, 1999, 297 (01) :103-110

[2]

Skeletal muscle myostatin mRNA expression is fiber-type specific and increases dining hindlimb unloading [J].

Carlson, CJ ;

Booth, FW ;

Gordon, SE .

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 1999, 277 (02) :R601-R606

[3]

SINGLE-STEP METHOD OF RNA ISOLATION BY ACID GUANIDINIUM THIOCYANATE PHENOL CHLOROFORM EXTRACTION [J].

CHOMCZYNSKI, P ;

SACCHI, N .

ANALYTICAL BIOCHEMISTRY, 1987, 162 (01) :156-159

[4]

CHOMCZYNSKI P, 1993, BIOTECHNIQUES, V15, P526

[5]

THE EFFECTS OF PROSTAGLANDINS, PHOSPHODIESTERASE INHIBITORS, AND CYCLIC-AMP ON OVULATION OF BROOK TROUT (SALVELINUS-FONTINALIS) OOCYTES [J].

GOETZ, FW ;

SMITH, DC ;

KRICKL, SP .

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 1982, 48 (02) :154-160

[6]

Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting [J].

Gonzalez-Cadavid, NF ;

Taylor, WE ;

Yarasheski, K ;

Sinha-Hikim, I ;

Ma, K ;

Ezzat, S ;

Shen, RQ ;

Lalani, R ;

Asa, S ;

Mamita, M ;

Nair, G ;

Arver, S ;

Bhasin, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (25) :14938-14943

[7]

A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle [J].

Grobet, L ;

Martin, LJR ;

Poncelet, D ;

Pirottin, D ;

Brouwers, B ;

Riquet, J ;

Schoeberlein, A ;

Dunner, S ;

Menissier, F ;

Massabanda, J ;

Fries, R ;

Hanset, R ;

Georges, M .

NATURE GENETICS, 1997, 17 (01) :71-74

[8]

Myostatin expression in porcine tissues: tissue specificity and developmental and postnatal regulation [J].

Ji, SQ ;

Losinski, RL ;

Cornelius, SG ;

Frank, GR ;

Willis, GM ;

Gerrard, DE ;

Depreux, FFS ;

Spurlock, ME .

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 1998, 275 (04) :R1265-R1273

[9]

Mutations in myostatin (GDF8) in double-muscled Belgian blue and Piedmontese cattle [J].

Kambadur, R ;

Sharma, M ;

Smith, TPL ;

Bass, JJ .

GENOME RESEARCH, 1997, 7 (09) :910-916

[10]

Kirk S, 2000, J CELL PHYSIOL, V184, P356, DOI 10.1002/1097-4652(200009)184:3<356::AID-JCP10>3.0.CO

← 1 2 3 →