Role of Kruppel-like transcription factors in endothelial biology

被引：355

作者：

Atkins, G. Brandon ^{[1
]}

Jain, Mukesh K. ^{[1
]}

机构：

[1] Case Western Reserve Univ, Case Cardiovasc Res Inst, Cleveland, OH 44106 USA

来源：

CIRCULATION RESEARCH | 2007年 / 100卷 / 12期

关键词：

endothelium; transcription; vessels; gene expression; gene regulation; FLUID SHEAR-STRESS; ZINC-FINGER PROTEIN; NITRIC-OXIDE SYNTHASE; NF-KAPPA-B; T-CELL QUIESCENCE; HEMODYNAMIC FORCES; GENE-EXPRESSION; BIOMECHANICAL ACTIVATION; VASCULAR ENDOTHELIUM; COUPLED RECEPTORS;

D O I：

10.1161/01.RES.0000267856.00713.0a

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Kruppel- like factors are members of the zinc finger family of transcription factors that have been implicated as playing key roles in regulating cellular differentiation and tissue development. Studies over the past several years support an important role for this family of factors in vascular biology. This review summarizes the role of Kruppel-like factors in endothelial cell biology.

引用

页码：1686 / 1695

页数：10

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