Successful treatment of pan-resistant Klebsiella pneumoniae pneumonia and bacteraemia with a combination of high-dose tigecycline and colistin

被引：55

作者：

Humphries, Romney M. ^{[1
]}

Kelesidis, Theodoros ^{[2
]}

Bard, Jennifer Dien ^{[1
]}

Ward, Kevin W. ^{[3
]}

Bhattacharya, Debika ^{[2
]}

Lewinski, Michael A. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Pathol & Lab Med, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Infect Dis, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, Med Ctr, Los Angeles, CA 90095 USA

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 2010年 / 59卷 / 11期

关键词：

ACINETOBACTER-BAUMANNII; MULTIDRUG-RESISTANT; ENTEROBACTERIACEAE; DISSEMINATION; INFECTIONS;

D O I：

10.1099/jmm.0.023010-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

The spread of antimicrobial resistance among members of the Enterobacteriaceae is a significant clinical threat. We report the treatment of pan-resistant Klebsiella pneumoniae bacteraemia with combination tigecycline and colistin in a 49-year-old male and review available therapeutic options. Despite a poor prognosis, the patient recovered, but remains colonized with the pan-resistant isolate.

引用

页码：1383 / 1386

页数：4

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