Novel cytotoxic kaurane-type diterpenoids from the New Zealand liverwort Jungermannia species

被引：47

作者：

Nagashima, F

Kondoh, M

Fujii, M

Takaoka, S

Watanabe, Y

Asakawa, Y

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan

[2] Showa Pharmaceut Univ, Dept Pharmaceut & Biopharmaceut, Machida, Tokyo 1948543, Japan

来源：

TETRAHEDRON | 2005年 / 61卷 / 19期

关键词：

Jungermannia; liverwort; Kaurane-type diterpenoid; cytotoxic;

D O I：

10.1016/j.tet.2005.03.010

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Novel cytotoxic rearranged kaurene- and ent-kaurene-type diterpenoids against HL-60 cells have been isolated from the unidentified New Zealand liverwort Jungermannia species together with previously known ent-kaurane-type diterpenoids. Their structures were determined by extensive NMR techniques, chemical degradation and X-ray crystallographic analysis. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4531 / 4544

页数：14

共 25 条

[1] Volatile components of selected species of the liverwort genera Frullania and Schusterella (Frullaniaceae) from New Zealand, Australia and South America:: a chemosystematic approach [J].