Matrix metalloproteinase8 has a central role in inflammatory disorders and cancer progression

被引：95

作者：

Dejonckheere, Eline ^{[1
,2
]}

Vandenbroucke, Roosmarijn E. ^{[1
,2
]}

Libert, Claude ^{[1
,2
]}

机构：

[1] VIB, DBMR, Dept Mol Biomed Res, B-9052 Ghent, Zwijnaarde, Belgium

[2] Univ Ghent, Dept Mol Biol, B-9000 Ghent, Belgium

来源：

CYTOKINE & GROWTH FACTOR REVIEWS | 2011年 / 22卷 / 02期

关键词：

MMP8; Inflammation; Cancer; GINGIVAL CREVICULAR FLUID; COLLAGENASE-2; MMP-8; EXPRESSION; IN-VIVO; TISSUE INHIBITOR; NEUTROPHIL COLLAGENASE; CHRONIC PERIODONTITIS; ADULT PERIODONTITIS; INDUCED SPUTUM; PLASMA-LEVELS; UP-REGULATION;

D O I：

10.1016/j.cytogfr.2011.02.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The predominant role of matrix metalloproteinase 8 in extracellular matrix turnover, modulation of inflammatory responses and other physiological processes is well documented. Several recent studies highlight the involvement of MMP8 in a wide range of pathologies. This review will shed light on the putative role of MMP8 as a drug target or disease marker in some inflammatory disorders and in cancer progression. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：73 / 81

页数：9

共 131 条

[1]

Collagen degradation in the abdominal aneurysm -: A conspiracy of matrix metalloproteinase and cysteine collagenases [J].

Abdul-Hussien, Hazem ;

Soekhoe, Ratna G. V. ;

Weber, Ekkehard ;

von der Thuesen, Jan H. ;

Kleemann, Robert ;

Mulder, Adri ;

van Bockel, J. Hajo ;

Hanemaaijer, Roeland ;

Lindeman, Jan H. N. .

AMERICAN JOURNAL OF PATHOLOGY, 2007, 170 (03) :809-817

[2]

Matrix metalloproteases and their tissue inhibitor in cardiac transplantation [J].

Aharinejad, Seyedhossein ;

Krenn, Katharina ;

Zuckermann, Andreas ;

Schaefer, Romana ;

Paulus, Patrick ;

Seebacher, Gernot ;

Wolner, Ernst ;

Grimm, Michael .

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2007, 32 (01) :48-51

[3]

Hypoxia upregulates angiogenesis and synovial cell migration in rheumatoid arthritis [J].

Akhavani, Mohammed A. ;

Madden, Leigh ;

Buysschaert, Ian ;

Sivakumar, Branavan ;

Kang, Norbert ;

Paleolog, Ewa M. .

ARTHRITIS RESEARCH & THERAPY, 2009, 11 (03)

[4]

ALBAICETA GM, 2009, AM J RESP CELL MOL B

[5]

Alfant B, 2008, J PERIODONTOL, V79, P819, DOI [10.1902/jop.2008.070513, 10.1902/jop.2008.070513 ]

[6]

Increased Expression of Metalloproteinase-8 and-13 on Articular Cartilage in a Rat Immobilized Knee Model [J].

Ando, Akira ;

Hagiwara, Yoshihiro ;

Tsuchiya, Masahiro ;

Onoda, Yoshito ;

Suda, Hideaki ;

Chimoto, Eiichi ;

Itoi, Eiji .

TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 2009, 217 (04) :271-278

[7]

Loss of collagenase-2 confers increased skin tumor susceptibility to male mice [J].

Balbín, M ;

Fueyo, A ;

Tester, AM ;

Pendás, AM ;

Pitiot, AS ;

Astudillo, A ;

Overall, CM ;

Shapiro, SD ;

López-Otín, C .

NATURE GENETICS, 2003, 35 (03) :252-257

[8]

Neutrophil granule proteins in bronchoalveolar lavage fluid from subjects with subclinical emphysema [J].

Betsuyaku, T ;

Nishimura, M ;

Takeyabu, K ;

Tanino, M ;

Venge, P ;

Xu, SY ;

Kawakami, Y .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (06) :1985-1991

[9]

Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage [J].

Billinghurst, RC ;

Dahlberg, L ;

Ionescu, M ;

Reiner, A ;

Bourne, R ;

Rorabeck, C ;

Mitchell, P ;

Hambor, J ;

Diekmann, O ;

Tschesche, H ;

Chen, J ;

VanWart, H ;

Poole, AR .

JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (07) :1534-1545

[10]

Wild-type versus mutant MMP-8 in melanoma: 'When you come to a fork in the road, take it' [J].

Blackburn, Jessica S. ;

Brinckerhoff, Constance E. .

PIGMENT CELL & MELANOMA RESEARCH, 2009, 22 (03) :248-250

← 1 2 3 4 5 6 7 8 9 10 →