Role and Regulation of Bacterial LuxR-Like Regulators

被引:93
作者
Chen, Jing [1 ]
Xie, Jianping [1 ]
机构
[1] Southwest Univ, Inst Modern Biopharmaceut, Sch Life Sci, Key Lab,Minist Educ Ecoenvironm Three Gorges Rese, Chongqing 400715, Peoples R China
关键词
LUXR; QUORUM SENSING; REGULATION; MYCOBACTERIUM; VIBRIO-HARVEYI-LUXR; QUORUM-SENSING REGULATOR; ENCODING GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE; STEWARTII SSP STEWARTII; CORYNEBACTERIUM-GLUTAMICUM; PSEUDOMONAS-AERUGINOSA; AEROMONAS-HYDROPHILA; GENE-EXPRESSION; STRUCTURAL IDENTIFICATION; DEPENDENT REGULATION;
D O I
10.1002/jcb.23219
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
LuxR transcriptional regulator is a key player in Quorum Sensing (QS), coordinates the expression of a variety of genes, including those encoding virulence factors and antibiotics biosynthesis, motility, nodulation, plasmid transfer, bioluminescence, and biofilm formation. The characteristics and roles of this family, especially those of Mycobacterium, are summarized in this paper to give clues for drug target discovery. J. Cell. Biochem. 112: 2694-2702, 2011. (C) 2011 Wiley-Liss, Inc.
引用
收藏
页码:2694 / 2702
页数:9
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