Ninety-six-week efficacy of combination therapy with lamivudine and tenofovir in patients coinfected with HIV-1 and wild-type hepatitis B virus

被引:44
作者
Bani-Sadr, F
Palmer, P
Scieux, C
Molina, JM
机构
[1] Hosp St Louis, Serv Malad Infect & Trop, Paris, France
[2] Hosp St Louis, Virol Lab, Paris, France
关键词
D O I
10.1086/424012
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We describe 6 patients who were coinfected with human immunodeficiency virus (HIV) type 1 and wild-type hepatitis B virus (HBV), in whom complete and sustained antiviral activity against wild-type HBV strains was attained during 96 weeks of combination therapy with lamivudine and tenofovir. The use of combination therapy with lamivudine and tenofovir for the treatment of HBV infection is very promising in the treatment of HIV/HBV coinfection.
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收藏
页码:1062 / 1064
页数:3
相关论文
共 5 条
[1]   Tenofovir disoproxil fumarate in patients with HIV and lamivudine-resistant hepatitis B virus. [J].
Benhamou, Y ;
Tubiana, R ;
Thibault, V .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (02) :177-178
[2]   Long-term incidence of hepatitis B virus resistance to lamivudine in human immunodeficiency virus-infected patients [J].
Benhamou, Y ;
Bochet, M ;
Thibault, V ;
Di Martino, V ;
Caumes, E ;
Bricaire, F ;
Opolon, P ;
Katlama, C ;
Poynard, T .
HEPATOLOGY, 1999, 30 (05) :1302-1306
[3]   An open-label study of tenofovir in HIV-1 and Hepatitis B virus co-infected individuals [J].
Nelson, M ;
Portsmouth, S ;
Stebbing, J ;
Atkins, M ;
Barr, A ;
Matthews, G ;
Pillay, D ;
Fisher, M ;
Bower, M ;
Gazzard, B .
AIDS, 2003, 17 (01) :F7-F10
[4]   Activity of tenofovir on hepatitis B virus replication in HIV-co-infected patients failing or partially responding to lamivudine [J].
Núñez, M ;
Pérez-Olmeda, M ;
Díaz, B ;
Ríos, P ;
González-Lahoz, J ;
Soriano, V .
AIDS, 2002, 16 (17) :2352-2354
[5]  
Ying C, 2000, J VIRAL HEPATITIS, V7, P161