Imaging in systems biology

被引:191
作者
Megason, Sean G. [1 ]
Fraser, Scott E.
机构
[1] CALTECH, Beckman Inst, Pasadena, CA 91125 USA
[2] CALTECH, Div Biol, Pasadena, CA 91125 USA
关键词
D O I
10.1016/j.cell.2007.08.031
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Most systems biology approaches involve determining the structure of biological circuits using genomewide "-omic" analyses. Yet imaging offers the unique advantage of watching biological circuits function over time at single-cell resolution in the intact animal. Here, we discuss the power of integrating imaging tools with more conventional-omic approaches to analyze the biological circuits of microorganisms, plants, and animals.
引用
收藏
页码:784 / 795
页数:12
相关论文
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