Trends in AIDS-related opportunistic infections among men who have sex with men and among injecting drug users, 1991-1996

被引：48

作者：

Jones, JL ^{[1
]}

Hanson, DL ^{[1
]}

Dworkin, MS ^{[1
]}

Kaplan, JE ^{[1
]}

Ward, JW ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Adult Adolescent Spectrum HIV Dis Grp, Div HIV AIDS Prevent Surveillance & Epidemiol, Natl Ctr HIV STD & TB Prevent, Atlanta, GA USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 1998年 / 178卷 / 01期

关键词：

D O I：

10.1086/515593

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Incidence trends for the 13 most frequent AIDS-defining opportunistic infections (OIs) among men who have sex with men (MSM, n = 15,588) and injecting drug users (IDUs, n = 4475) were examined using data abstracted from medical records in >90 hospitals and clinics in nine US cities during 1991-1996, Among MSM, the most frequent OIs were Mycobacterium avium complex (MAC) disease, Pneumocystis carinii pneumonia (PCP), and cytomegalovirus (CMV) retinitis; decreasing (P less than or equal to.05) trends occurred for 11 OIs (MAC disease, PCP, CMV retinitis, Kaposi's sarcoma, esophageal candidiasis, CMV disease, extrapulmonary cryptococcosis, toxoplasmic encephalitis, tuberculosis, chronic herpes simplex, and disseminated histoplasmosis). Among IDUs, the most frequent OIs were PCP, MAC disease, and esophageal candidiasis; decreasing trends occurred for 5 OIs (PCP, esophageal candidiasis, tuberculosis, chronic herpes simplex, and chronic cryptosporidiosis) and an increase occurred in recurrent pneumonia. The differences in trends for MSM and IDUs may be due to differences in medical fare and adherence to preventive medications.

引用

页码：114 / 120

页数：7

共 29 条

[1]

[Anonymous], MMWR MORB MORTAL WKL

[2]

[Anonymous], 1992, MMWR-MORBID MORTAL W, V41, P1

[3] A RANDOMIZED TRIAL OF 3 ANTIPNEUMOCYSTIS AGENTS IN PATIENTS WITH ADVANCED HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION [J].

BOZZETTE, SA ;

FINKELSTEIN, DM ;

SPECTOR, SA ;

FRAME, P ;

POWDERLY, WG ;

HE, WL ;

PHILLIPS, L ;

CRAVEN, D ;

VANDERHORST, C ;

FEINBERG, J .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (11) :693-699

[4]

*CDCP, 1997, REP TUB US 1996, V5

[5]

*CDCP, 1992, MMWR-MORBID MORTAL W, V41, P4

[6]

Centers for Disease Control and Prevention (CDC), 1993, MMWR Morb Mortal Wkly Rep, V42, P14

[7]

Centers for Disease Control (CDC), 1989, MMWR Suppl, V38, P1

[8] SPECTRUM OF DISEASE IN PERSONS WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION IN THE UNITED-STATES [J].

FARIZO, KM ;

BUEHLER, JW ;

CHAMBERLAND, ME ;

WHYTE, BM ;

FROELICHER, ES ;

HOPKINS, SG ;

REED, CM ;

MOKOTOFF, ED ;

COHN, DL ;

TROXLER, S ;

PHELPS, AF ;

BERKELMAN, RL .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1992, 267 (13) :1798-1805

[9]

Gindler J. S., 1995, Morbidity and Mortality Weekly Report, V44, P1

[10]

GREEN TA, 1992, J ACQ IMMUN DEF SYND, V5, P547

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