The development of molecular fluorescent switches

被引：102

作者：

de Silva, AP ^{[1
]}

Fox, DB ^{[1
]}

Moody, TS ^{[1
]}

Weir, SM ^{[1
]}

机构：

[1] Queens Univ Belfast, Sch Chem, Belfast BT9 5AG, Antrim, North Ireland

来源：

TRENDS IN BIOTECHNOLOGY | 2001年 / 19卷 / 01期

关键词：

D O I：

10.1016/S0167-7799(00)01513-4

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Molecular systems in which fluorescence switches between 'on' and 'off' states when driven by chemical stimuli can be designed according to a few principles. The photochemical mechanisms examined are photoinduced electron transfer, internal charge transfer and excimer formation, with emphasis on the first category. These designs open the way to sharp signalling of small chemical species that perform critical biological functions.

引用

页码：29 / 34

页数：6

共 25 条

[1] BALZNI V, 1991, SUPRAMOLECULAR PHOTO
[2] MOLECULAR FLUORESCENT SIGNALING WITH FLUOR SPACER RECEPTOR SYSTEMS - APPROACHES TO SENSING AND SWITCHING DEVICES VIA SUPRAMOLECULAR PHOTOPHYSICS
BISSELL, RA
DE SILVA, AP
GUNARATNE, HQN
LYNCH, PLM
MAGUIRE, GEM
SANDANAYAKE, KRAS
[J]. CHEMICAL SOCIETY REVIEWS, 1992, 21 (03) : 187 - 195
[3] BISSELL RA, 1993, TOP CURR CHEM, V168, P228
[4] CATION-DIRECTED PHOTOCHEMISTRY OF AN ANTHRACENO-CROWN ETHER
BOUASLAURENT, H
CASTELLAN, A
DANEY, M
DESVERGNE, JP
GUINAND, G
MARSAU, P
RIFFAUD, MH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (02) : 315 - 317
[5] Czarnik A.W., 1997, Chemosensors for Ion and Molecular Recognition
[6] DESPERATELY SEEKING SENSORS
CZARNIK, AW
[J]. CHEMISTRY & BIOLOGY, 1995, 2 (07): : 423 - 428
[7] A MOLECULAR PHOTOIONIC AND GATE BASED ON FLUORESCENT SIGNALING
DE SILVA, AP
GUNARATNE, HQN
MCCOY, CP
[J]. NATURE, 1993, 364 (6432) : 42 - 44
[8] Molecular photoionic and logic gates with bright fluorescence and ''off-on'' digital action
de Silva, AP
Gunaratne, HQN
McCoy, CP
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (33) : 7891 - 7892
[9] A NEW CLASS OF FLUORESCENT PH INDICATORS BASED ON PHOTOINDUCED ELECTRON-TRANSFER
DE SILVA, AP
RUPASINGHE, RADD
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1985, (23) : 1669 - 1670
[10] Direct visual indication of pH windows: 'Off-on-off' fluorescent PET (photoinduced electron transfer) sensors switches
de Silva, AP
Gunaratne, HQN
McCoy, CP
[J]. CHEMICAL COMMUNICATIONS, 1996, (21) : 2399 - 2400

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