Contact cooling of the skin

被引:73
作者
Altshuler, GB
Zenzie, HH
Erofeev, AV
Smirnov, MZ
Anderson, RR
Dierickx, C
机构
[1] Palomar Med Prod Inc, Lexington, MA 02173 USA
[2] Inst Fine Mech, St Petersburg 197101, Russia
[3] Opt Laser Ctr, St Petersburg 197101, Russia
[4] Massachusetts Gen Hosp, Wellman Labs Photomed, Boston, MA 02114 USA
关键词
D O I
10.1088/0031-9155/44/4/014
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Skin precooling can be used to reduce epidermal thermal damage in laser procedures (such as hair removal) where the target structures are located up to several millimetres below the skin surface. We have developed and experimentally verified a computational model that describes contact precooling of a multilayered skin structure prior to laser irradiation. The skin surface is assumed to be brought into thermal contact with a cold plate made of material with a high thermal conductivity. The approximate analytical solution for the skin temperature is obtained by considering the plate as a local heat sink. The time evolution of temperature (in both the skin and the plate) is simulated numerically to yield the optimal cooling parameters. To experimentally verify the numerical results of the model, we performed direct measurements of skin temperature for contact cooling with a sapphire plate held at several different temperatures in the range +10 to -30 degrees C.
引用
收藏
页码:1003 / 1023
页数:21
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