The role of salicylic acid in the induction of cell death in Arabidopsis acd11

被引：116

作者：

Brodersen, P

Malinovsky, FG

Hématy, K

Newman, MA

Mundy, J ^{[1
]}

机构：

[1] Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen, Denmark

[2] Royal Vet & Agr Univ, Inst Plant Biol, DK-1871 Frederiksberg, Denmark

来源：

PLANT PHYSIOLOGY | 2005年 / 138卷 / 02期

关键词：

D O I：

10.1104/pp.105.059303

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Salicylic acid (SA) is implicated in the induction of programmed cell death (PCD) associated with pathogen defense responses because SA levels increase in response to PCD-inducing infections, and PCD development can be inhibited by expression of salicylate hydroxylase encoded by the bacterial nahG gene. The acd11 mutant of Arabidopsis ( Arabidopsis thaliana L. Heynh.) activates PCD and defense responses that are fully suppressed by nahG. To further study the role of SA in PCD induction, we compared phenotypes of acd11/nahG with those of acd11/eds5-1 and acd11/sid2-2 mutants deficient in a putative transporter and isochorismate synthase required for SA biosynthesis. We show that sid2-2 fully suppresses SA accumulation and cell death in acd11, although growth inhibition and premature leaf chlorosis still occur. In addition, application of exogenousSA to acd11/sid2-2 is insufficient to restore cell death. This indicates that isochorismate- derived compounds other than SA are required for induction of PCD in acd11 and that some acd11 phenotypes require NahG-degradable compounds not synthesized via isochorismate.

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页码：1037 / 1045

页数：9

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