Study on antibacterial mechanism of copper-bearing austenitic antibacterial stainless steel by atomic force microscopy

被引：192

作者：

Nan, Li ^{[1
,2
]}

Liu, Yongqian ^{[1
,2
]}

Lue, Manqi ^{[1
]}

Yang, Ke ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 2008年 / 19卷 / 09期

关键词：

D O I：

10.1007/s10856-008-3444-z

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

A study was made on the antibacterial mechanism of copper-bearing austenitic antibacterial stainless steel by a series of methods such as atomic force microscopy (AFM) observation, force-distance curves and inductively coupled plasma mass spectrometer test. It was observed by AFM that the structure of the outer cell membrane responsible for the cell permeability was substantially changed for the bacteria after contacting with the antibacterial stainless steel, showing that cell walls were seriously damaged and a lot of contents in the cells leaked. It was also found that the adhesion force of bacteria to antibacterial stainless steel was considerably greater than that to the contrast steel, indicating that the electrostatic forces by Cu2+ being an important factor for killing bacteria.

引用

页码：3057 / 3062

页数：6

共 26 条

[1]

High-resolution atomic force microscopy studies of the Escherichia coli outer membrane:: Structural basis for permeability [J].