Kawasaki Disease: An Update on Diagnosis and Treatment

被引：136

作者：

Kuo, Ho-Chang ^{[3
,4
]}

Yang, Kuender D. ^{[5
]}

Chang, Wei-Chiao ^{[6
]}

Ger, Luo-Ping ^{[7
]}

Hsieh, Kai-Sheng ^{[1
,2
]}

机构：

[1] Kaohsiung Vet Gen Hosp, Dept Pediat, Kaohsiung 813, Taiwan

[2] Natl Yang Ming Univ, Taipei, Taiwan

[3] Kaohsiung Chang Gung Mem Hosp, Dept Pediat, Div Allergy Immunol & Rheumatol, Kaohsiung, Taiwan

[4] Chang Gung Univ, Coll Med, Kaohsiung, Taiwan

[5] Show Chwan Mem Hosp Chang Bing, Dept Med Res, Changhua, Taiwan

[6] Kaohsiung Med Univ, Dept Med Genet, Kaohsiung, Taiwan

[7] Kaohsiung Vet Gen Hosp, Dept Med Educ, Kaohsiung 813, Taiwan

来源：

PEDIATRICS AND NEONATOLOGY | 2012年 / 53卷 / 01期

关键词：

coronary artery lesion; IVIG; Kawasaki disease; INTRAVENOUS IMMUNOGLOBULIN TREATMENT; CORONARY-ARTERY LESIONS; GAMMA-GLOBULIN TREATMENT; EPIDEMIOLOGIC FEATURES; GENETIC POLYMORPHISMS; TREATMENT FAILURE; METHYLPREDNISOLONE PULSE; INFLIXIMAB TREATMENT; IMMUNE GLOBULIN; INFANTS YOUNGER;

D O I：

10.1016/j.pedneo.2011.11.003

中图分类号：

R72 [儿科学];

学科分类号：

100202 [儿科学];

摘要：

Kawasaki disease (KD) is an acute multi-system vasculitis syndrome of unknown etiology occurring mostly in infants and children younger than 5 years of age. In developed countries, it is the leading cause of acquired heart disease in children. However, KD remains a mysterious disease. Some viruses potentially causing the condition have been isolated, but the results have not been able to be reproduced. This article reviews and summarizes different aspects of KD and provides updated information on diagnosis and treatment. The supplementary criteria for incomplete presentation of KD patients suggested by the American Heart Association, treatment (including tumor necrosis factor-alpha antagonist, methylprednisolone pulse therapy, statins, plasma exchange, and cytotoxic agents) for those with intravenous immunoglobulin treatment failure, and other experiences are also included in this review. Copyright (C) 2012, Taiwan Pediatric Association. Published by Elsevier Taiwan LLC. All rights reserved.

引用

页码：4 / 11

页数：8

共 95 条

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[2]

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