Novel beta(3) isoform of the Na,K-ATPase beta subunit from mouse retina

被引：18

作者：

Besirli, CG ^{[1
]}

Gong, TWL ^{[1
]}

Lomax, MI ^{[1
]}

机构：

[1] UNIV MICHIGAN, SCH MED, DEPT OTOLARYNGOL HEAD & NECK SURG, KRESGE HEARING RES INST, ANN ARBOR, MI 48109 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1997年 / 1350卷 / 01期

关键词：

ATPase; Na+/K+-; beta subunit; cDNA sequence; evolution; sodium pump;

D O I：

10.1016/S0167-4781(96)00192-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

We isolated a full-length cDNA encoding a novel 278 amino acid beta subunit of Na,K-ATPase from a mouse retinal cDNA library. The highest sequence identity was to known beta(3) isoforms, identifying the protein as the mouse beta(3) subunit of Na, K-ATPase. Two transcripts, 1.75 kb and 2.1 kb, probably arise from use of alternative poly(A) addition signals.

引用

收藏

页码：21 / 26

页数：6

相关论文

共 22 条

[1]

ALTSCHUL SF, 1990, J MOL BIOL, V215, P403, DOI 10.1006/jmbi.1990.9999

[2]

SINGLE-STEP METHOD OF RNA ISOLATION BY ACID GUANIDINIUM THIOCYANATE PHENOL CHLOROFORM EXTRACTION [J].

CHOMCZYNSKI, P ;

SACCHI, N .

ANALYTICAL BIOCHEMISTRY, 1987, 162 (01) :156-159

[3]

EAKLE KA, 1994, J BIOL CHEM, V269, P6550

[4]

THE INFLUENCE OF BETA-SUBUNIT STRUCTURE ON THE INTERACTION OF NA+/K+-ATPASE COMPLEXES WITH NA+ - A CHIMERIC BETA-SUBUNIT REDUCES THE NA+ DEPENDENCE OF PHOSPHOENZYME FORMATION FROM ATP [J].

EAKLE, KA ;

LYU, RM ;

FARLEY, RA .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (23) :13937-13947

[5]

MOLECULAR CHARACTERIZATION OF THE MURINE NEURAL RETINA LEUCINE-ZIPPER GENE, NRL [J].

FARJO, Q ;

JACKSON, AU ;

XU, JZ ;

GRYZENIA, M ;

SKOLNICK, C ;

AGARWAL, N ;

SWAROOP, A .

GENOMICS, 1993, 18 (02) :216-222

[6]

A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY [J].

FEINBERG, AP ;

VOGELSTEIN, B .

ANALYTICAL BIOCHEMISTRY, 1983, 132 (01) :6-13

[7]

SUBUNIT ASSEMBLY AND FUNCTIONAL MATURATION OF NA,K-ATPASE [J].

GEERING, K .

JOURNAL OF MEMBRANE BIOLOGY, 1990, 115 (02) :109-121

[8]

THE ADHESION MOLECULE ON GLIA (AMOG) IS A HOMOLOG OF THE BETA-SUBUNIT OF THE NA,K-ATPASE [J].

GLOOR, S ;

ANTONICEK, H ;

SWEADNER, KJ ;

PAGLIUSI, S ;

FRANK, R ;

MOOS, M ;

SCHACHNER, M .

JOURNAL OF CELL BIOLOGY, 1990, 110 (01) :165-174

[9]

Identification of genes expressed after noise exposure in the chick basilar papilla [J].

Gong, TWL ;

Hegeman, AD ;

Shin, JJ ;

Adler, HJ ;

Raphael, Y ;

Lomax, MI .

HEARING RESEARCH, 1996, 96 (1-2) :20-32

[10]

A NERVOUS SYSTEM-SPECIFIC ISOTYPE OF THE BETA-SUBUNIT OF NA+,K+-ATPASE EXPRESSED DURING EARLY DEVELOPMENT OF XENOPUS-LAEVIS [J].

GOOD, PJ ;

RICHTER, K ;

DAWID, IB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (23) :9088-9092