Measurements of the phase behaviour of the system dextran/DMSO/CO2 at high pressures

被引:16
作者
de Diego, YN
Wubbolts, E
Witkamp, GJ
de Loos, TW
Jansens, P
机构
[1] Delft Univ Technol, Lab Proc Equip, NL-2628 CA Delft, Netherlands
[2] Delft Univ Technol, NL-2628 BL Delft, Netherlands
关键词
polymer; carbon dioxide; ternary phase diagram; liquid-liquid phase split;
D O I
10.1016/j.supflu.2004.10.012
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
This paper deals with the measurements of the phase behaviour at high pressures of the system dextran/dimethylsulphoxide/CO2, a system that is being used to study the micronisation of biodegradable polymers using the PCA process. The study of the phase behaviour has been performed combining two independent measurement techniques. It will be shown that the variable composition view cell method recently developed [1] is a useful, easy and reliable method that can be applied to study polymer systems. It can be used to determine the amount Of CO2 needed to induce a liquid-liquid phase split in the polymer solution within a 1-2 wt.% error. However, this method was not sensitive enough to predict how the studied system reacts to moderate changes in pressure and temperature. The Cailletet tube method was used to obtain more accurate PT data (isopleths) to complete the information on the phase behaviour of the system. The influence on the PT phase behaviour of the concentration Of CO2, the concentration of dextran as well as the presence of water in the system was studied. (c) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:1 / 9
页数:9
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