The incidence of motor nueron disease in Scotland

被引:73
作者
Forbes, Raeburn B. [1 ]
Colville, Shuna [1 ]
Parratt, John [1 ]
Swingler, Robert J. [1 ]
机构
[1] Univ Dundee, Ninewells Hosp & Med Sch, Dept Neurol, Dundee DD1 9SY, Scotland
关键词
motor neuron disease; amyotrophic lateral sclerosis; epidemiology and ascertainment;
D O I
10.1007/s00415-006-0454-y
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Between 1989 and 1998, 1226 cases of ALS/MND were identified in Scotland, with mean age of onset 65.2 (SD 11.9) years for men and 67.2 (SD 11.0) for women. Annual standardized incidence was 2.40 per 100,000 (95% CI 2.22-2.58). Using capture recapture methods we confirm a high level of case ascertainment for each year of study. Incidence and ascertainment of ALS has remained stable in a large population over a prolonged period of time. Large population-based databases can be used to test aetiological hypotheses.
引用
收藏
页码:866 / 869
页数:4
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