Aβ peptide deposition in the brains of transgenic mice:: evidence for a key event in Alzheimer's disease pathogenesis

被引：7

作者：

Sommer, B ^{[1
]}

Staufenbiel, M ^{[1
]}

机构：

[1] Novartis Pharma Inc, Nervous Syst Res, CH-4002 Basel, Switzerland

来源：

MOLECULAR PSYCHIATRY | 1998年 / 3卷 / 04期

关键词：

D O I：

10.1038/sj.mp.4000397

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transgenic technology has led to the generation of several animal models for Alzheimer's disease. These transgenic mice surprisingly reproduce many aspects of the pathological alterations observed in Alzheimer's disease patients.

引用

页码：284 / 286

页数：3

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