Transcriptional regulation of the human apolipoprotein genes

被引：60

作者：

Zannis, VI

Kan, HY

Kritis, A

Zanni, E

Kardassis, D

机构：

[1] Boston Univ, Sch Med, Mol Genet Sect, Whitaker Cardiovasc Inst,Dept Med, Boston, MA 02118 USA

[2] Boston Univ, Sch Med, Mol Genet Sect, Whitaker Cardiovasc Inst,Dept Biochem, Boston, MA 02118 USA

[3] Univ Crete, Dept Biochem, Iraklion 71110, Crete, Greece

[4] Inst Mol Biol & Biotechnol, Iraklion 71110, Crete, Greece

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2001年 / 6卷

关键词：

lipoproteins; apoproteins; apoA-I; apoA-II; apoA-IV; apoB; apoCI; apoCII; apoCIII; apoE; basal transcription complex; transcription factors; HNF-4; hormone nuclear receptors (PPAR; RXR; RAR; T3R beta); SP1; SREBP-1; SREBP-2; USF; ATF-2; Jun; SMAD; promoters; enhancers; transcriptional activation; transcriptional synergism; tissue-specific transcription; transgenic mice; signaling pathways (NF kappa B; SAPK/JNK; MAPK);

D O I：

10.2741/Zannis

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review provides experiments and putative mechanisms which underlie the transcription of the human apolipoprotein genes in vitro and in vivo. Summarized below are the key findings for individual genes and gene clusters.

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收藏

页码：D456 / D504

页数：49

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