Cryptococcus neoformans galactoxylomannan contains an epitope(s) that is cross-reactive with Aspergillus galactomannan

被引:68
作者
Dalle, F
Charles, PE
Blanc, K
Caillot, D
Chavanet, P
Dromer, F
Bonnin, A
机构
[1] Hop Bocage, CHU, Lab Parasitol Mycol, F-21079 Dijon, France
[2] Fac Med Dijon, Lab Microbiol Med & Mol, F-21079 Dijon, France
[3] Hop Enfants, CHU, Serv Maladies Infect & Trop, Dijon, France
[4] Hop Enfants, CHU, Serv Hematol Clin, Dijon, France
[5] Inst Pasteur, Ctr Natl Reference Mycol & Antifong, Paris, France
关键词
D O I
10.1128/JCM.43.6.2929-2931.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We report a case of cryptococcosis in which a serum enzyme-linked immunosorbent assay (ELISA) for Aspergillus galactomannan was positive, with no evidence of aspergillosis. Soluble antigens from 19 Cryptococcus neoformans strains and purified carbohydrates of C neoformans capsule were thus assayed in the Aspergillus galactomannan ELISA. Antigens from all C. neoformans strains, and purified galactoxylomannan, gave a positive reaction, suggesting that C neoformans galactoxylomannan contains an epitope(s) that is cross-reactive with Aspergillus galactomannan.
引用
收藏
页码:2929 / 2931
页数:3
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