Five new eudesmane-type sesquiterpenoids from Chinese agarwood induced by artificial holing

被引：60

作者：

Li, Wei ^{[1
]}

Cai, Cai-Hong ^{[1
]}

Guo, Zhi-Kai ^{[1
]}

Wang, Hao ^{[1
]}

Zuo, Wen-Jian ^{[1
]}

Dong, Wen-Hua ^{[1
]}

Mei, Wen-Li ^{[1
]}

Dai, Hao-Fu ^{[1
]}

机构：

[1] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Hainan, Peoples R China

来源：

FITOTERAPIA | 2015年 / 100卷

关键词：

Agarwood induced by artificial holing; Aquilaria sinensis (Lour.) Gilg; Thymelaeaceae; Sesquiterpenoids; Antibacterial activities; AChE inhibitory activities; 2-(2-PHENYLETHYL)CHROMONE DERIVATIVES; AQUILARIA-SINENSIS; QI-NAN; EAGLEWOOD;

D O I：

10.1016/j.fitote.2014.11.010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Five new eudesmane-type sesquiterpenoids (1-5), along with six known ones (6-11), were isolated from Chinese agarwood induced by artificial holing originating from Aquilaria sinensis (Lour.) Gilg (Thymelaeaceae). The structures of the new sesquiterpenoids were established by spectroscopic methods including UV, IR, MS, 1D, and 2D NMR. Compounds 1, 3, 6 and 7 exhibited antibacterial activities against both Staphylococcus aureus and Ralstonia solanacearum, and compound 5 only showed an inhibitory activity towards S. aureus. Compounds 1, 6, 7 and 10 showed weak acetylcholinesterase inhibitory activity. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：44 / 49

页数：6

共 25 条

[1] NATURALLY-OCCURRING TERPENES DERIVATIVES .265. NEW SESQUITERPENE AND NORDITERPENES FROM SPECIES OF LIBANOTHAMNUS [J].