Regulating transgenic crops sensibly: lessons from plant breeding, biotechnology and genomics

被引:145
作者
Bradford, KJ
Van Deynze, A
Gutterson, N
Parrott, W
Strauss, SH
机构
[1] Oregon State Univ, Dept Forest Sci, Corvallis, OR 97331 USA
[2] Univ Calif Davis, Seed Biotechnol Ctr, Davis, CA 95616 USA
[3] Mendel Biotechnol Inc, Hayward, CA 94545 USA
[4] Univ Georgia, Dept Crop & Soil Sci, Athens, GA 30602 USA
关键词
D O I
10.1038/nbt1084
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The costs of meeting regulatory requirements and market restrictions guided by regulatory criteria are substantial impediments to the commercialization of transgenic crops. Although a cautious approach may have been prudent initially, we argue that some regulatory requirements can now be modified to reduce costs and uncertainty without compromising safety. Long-accepted plant breeding methods for incorporating new diversity into crop varieties, experience from two decades of research on and commercialization of transgenic crops, and expanding knowledge of plant genome structure and dynamics all indicate that if a gene or trait is safe, the genetic engineering process itself presents little potential for unexpected consequences that would not be identified or eliminated in the variety development process before commercialization. We propose that as in conventional breeding, regulatory emphasis should be on phenotypic rather than genomic characteristics once a gene or trait has been shown to be safe.
引用
收藏
页码:439 / 444
页数:6
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