Enantioselective synthesis of arylamines through Zr-catalyzed addition of dialkylzincs to imines. Reaction development by screening of parallel libraries

被引:139
作者
Porter, JR [1 ]
Traverse, JF [1 ]
Hoveyda, AH [1 ]
Snapper, ML [1 ]
机构
[1] Boston Coll, Dept Chem, Merkert Chem Ctr, Chestnut Hill, MA 02467 USA
关键词
D O I
10.1021/ja003747y
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
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页码:984 / 985
页数:2
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共 31 条
  • [1] β-amino esters via the Reformatsky reaction:: Restraining effects of the ortho-methoxyphenyl substituent
    Adrian, JC
    Barkin, JL
    Hassib, L
    [J]. TETRAHEDRON LETTERS, 1999, 40 (13) : 2457 - 2460
  • [2] Preparation and use of aziridino alcohols as promoters for the enantioselective addition of dialkylzinc reagents to N-(diphenylphosphinoyl) imines
    Andersson, PG
    Guijarro, D
    Tanner, D
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (21) : 7364 - 7375
  • [3] A new multicomponent synthesis of 1,2,3,4-tetrahydroquinolines
    Annunziata, R
    Cinquini, M
    Cozzi, F
    Molteni, V
    Schupp, O
    [J]. TETRAHEDRON, 1997, 53 (28) : 9715 - 9726
  • [4] BHATTARAI K, 1990, SYNLETT, P229
  • [5] Additions of organometallic reagents to C=N bonds: Reactivity and selectivity
    Bloch, R
    [J]. CHEMICAL REVIEWS, 1998, 98 (04) : 1407 - 1438
  • [6] Asymmetric synthesis of α,α-dibranched amines by the trimethylaluminum-mediated 1,2-addition of organolithiums to tert-butanesulfinyl ketimines
    Cogan, DA
    Ellman, JA
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (01) : 268 - 269
  • [7] Discovery of chiral catalysts through ligand diversity: Ti-catalyzed enantioselective addition of TMSCN to meso epoxides
    Cole, BM
    Shimizu, KD
    Krueger, CA
    Harrity, JPA
    Snapper, ML
    Hoveyda, AH
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1996, 35 (15): : 1668 - 1671
  • [8] DEGRADO SJ, IN PRESS J AM CHEM S
  • [9] Denmark S. E., 1996, J CHEM SOC CHEM COMM, P999
  • [10] ASYMMETRIC ADDITION OF ORGANOLITHIUM REAGENTS TO IMINES
    DENMARK, SE
    NAKAJIMA, N
    NICAISE, OJC
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (19) : 8797 - 8798