CD24: a genetic checkpoint in T cell homeostasis and autoimmune diseases

被引：61

作者：

Liu, Yang ^{[1
]}

Zheng, Pan ^{[1
]}

机构：

[1] Univ Michigan, Dept Surg, Div Immunotherapy, Ann Arbor, MI 48109 USA

来源：

TRENDS IN IMMUNOLOGY | 2007年 / 28卷 / 07期

关键词：

D O I：

10.1016/j.it.2007.05.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

CD24 is widely used as a marker for differentiation of multiple lineages of cells and can provide costimulation for T cells, especially in non-lymphoid target organs. Recent studies demonstrate that CD24 controls an important genetic checkpoint for homeostasis and autoimmune diseases in both mice and humans. Understanding the molecular and cellular basis of CD24 function could provide important insights into T cell biology and autoimmunity.

引用

页码：315 / 320

页数：6

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