Biaryl synthesis via palladium-catalyzed aryne multicomponent coupling

被引：56

作者：

Henderson, Jaclyn L. ^{[1
]}

Edwards, Andrew S. ^{[2
]}

Greaney, Michael F. ^{[1
]}

机构：

[1] Univ Edinburgh, Sch Chem, Edinburgh EH9 3JJ, Midlothian, Scotland

[2] Organon Res Labs Ltd, Newhouse ML1 5SH, Lanark, Scotland

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 26期

关键词：

D O I：

10.1021/ol702584t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aryl iodides have been introduced as electrophiles in the three-component Heck coupling of arynes. Following optimization studies to favor three- versus two-component coupling, the reaction proceeds in good yield to afford a variety of functionalized biaryls.

引用

页码：5589 / 5592

页数：4

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