Energy use by biological protein transport pathways

被引：28

作者：

Alder, NN

Theg, SM ^{[1
]}

机构：

[1] Univ Calif Davis, Plant Biol Sect, Div Biol Sci, Davis, CA 95616 USA

[2] Texas A&M Univ Syst, Hlth Sci Ctr, Dept Med Biochem & Genet, College Stn, TX 77843 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2003年 / 28卷 / 08期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0968-0004(03)00167-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The targeting of proteins into and across biological membranes to their correct cellular locations is mediated by a variety of transport pathways. These systems must couple the thermodynamically unfavorable processes of substrate translocation and integration with the expenditure of metabolic energy, using the free energy of ATP and GTP hydrolysis and/or a transmembrane protonmotive force. Several recent advances in our knowledge of the structure and function of these transport systems have provided insights into the mechanisms of energy transduction, force generation and energy use by different protein transport pathways.

引用

页码：442 / 451

页数：10

共 75 条

[1] Energetics of protein transport across biological membranes:: A study of the thylakoid ΔpH-dependent/cpTat pathway [J].