Insulin-like 6 immunoreactivity in the mouse brain and testis

被引：13

作者：

Brailoiu, GC

Dun, SL

Yin, DL

Yang, J

Chang, JK

Dun, NJ

机构：

[1] Temple Univ, Sch Med, Dept Pharmacol, Philadelphia, PA 19140 USA

[2] E Tennessee State Univ, James H Quillen Coll Med, Dept Internal Med, Johnson City, TN 37614 USA

[3] Phoenix Pharmaceut Inc, Belmont, CA 94002 USA

来源：

BRAIN RESEARCH | 2005年 / 1040卷 / 1-2期

关键词：

insulin-like growth factor; Leydig cells; arcuate nucleus; caudal hypothalamus; dorsal raphe nuclei; tuberomammillary nuclei;

D O I：

10.1016/j.brainres.2005.01.077

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Insulin-like 6 immunoreactivity (irlNSL6) was detected in Leydig cells of the mouse testis. In the brain, labeled somata were detected mainly in the caudal hypothalamus and midbrain. Double labeling the brainstem sections revealed that irlNSL6 somata were 5-hydroxytryptamine (5-HT) positive. The presence of irlNSL6 in discrete Populations of hypothalamic and brainstem neurons and in Leydig cells of the testis suggests a diverse biological function of this novel peptide. (c) 2005 Elsevier B.V. All rights reserved.

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收藏

页码：187 / 190

页数：4

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