Evaluating cluster alarms: A space-time scan statistic and brain cancer in Los Alamos, New Mexico

被引：486

作者：

Kulldorff, M

Athas, WF

Feuer, EJ

Miller, BA

Key, CR

机构：

[1] NCI, Div Canc Prevent, Bethesda, MD 20892 USA

[2] NCI, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA

[3] Uppsala Univ, Dept Stat, Uppsala, Sweden

[4] New Mexico Dept Hlth, Div Epidemiol Evaluat & Planning, Santa Fe, NM USA

[5] Univ New Mexico, New Mexico Tumor Registry, Ctr Canc, Albuquerque, NM 87131 USA

来源：

AMERICAN JOURNAL OF PUBLIC HEALTH | 1998年 / 88卷 / 09期

关键词：

D O I：

10.2105/AJPH.88.9.1377

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objectives. This article presents a space-time scan statistic, useful for evaluating space-time cluster alarms, and illustrates the method on a recent brain cancer cluster alarm in Los Alamos, NM. Methods. The space-time scan statistic accounts for the preselection bias and multiple testing inherent in a cluster alarm. Confounders and time trends can be adjusted for Results. The observed excess of brain cancer in Los Alamos was not statistically significant. Conclusions. The space-time scan statistic is useful as a screening tool for evaluating which cluster alarms merit further investigation and which clusters are probably chance occurrences.

引用

页码：1377 / 1380

页数：4

共 23 条

[1]

[Anonymous], SEER CANC STAT REV 1

[2]

ATHAS WF, 1993, LOS ALAMOS CANC RATE

[3] ANALYZING POST-ALARM DATA IN A MONITORING-SYSTEM IN ORDER TO ACCEPT OR REJECT THE ALARM [J].