Foxa2: The rise and fall of dopamine neurons

被引：31

作者：

Arenas, Ernest ^{[1
]}

机构：

[1] Karolinska Inst, Mol Neurobiol Lab, MBB, Ctr Excellence Dev Biol, S-17177 Stockholm, Sweden

来源：

CELL STEM CELL | 2008年 / 2卷 / 02期

关键词：

D O I：

10.1016/j.stem.2008.01.012

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Understanding the development and maintenance of dopamine neurons is essential to establish novel stem cell therapies and animal models of Parkinson's disease. A recent PLoS Biology report (Kittappa et al., 2007) reveals that Foxa2 regulates dopamine neuron generation and differentiation, and that aging foxa(2+/-) mice spontaneously develop Parkinsonism.

引用

收藏

页码：110 / 112

页数：3

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