PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases

被引：114

作者：

Pawlowski, K

Pio, F

Chu, ZL

Reed, JC

Godzik, A

机构：

[1] Burnham Inst, Program Bioinformat & Biol Complex, La Jolla, CA 92037 USA

[2] Simon Fraser Univ, MBB Dept, Burnaby, BC V5A 1S6, Canada

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2001年 / 26卷 / 02期

关键词：

D O I：

10.1016/S0968-0004(00)01729-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new protein domain was found in several proteins involved in apoptosis, inflammation, cancer and immune responses. Its location within these proteins and predicted fold suggests that it functions as a protein-protein interaction domain, possibly uniting different signaling pathways.

引用

页码：85 / 87

页数：3

共 20 条

[1] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
Altschul, SF
Madden, TL
Schaffer, AA
Zhang, JH
Zhang, Z
Miller, W
Lipman, DJ
[J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (17) : 3389 - 3402
[2] The domains of death: evolution of the apoptosis machinery
Aravind, L
Dixit, VM
Koonin, EV
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1999, 24 (02) : 47 - 53
[3] Bernot A, 1997, NAT GENET, V17, P25
[4] Prediction of complete gene structures in human genomic DNA
Burge, C
Karlin, S
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1997, 268 (01) : 78 - 94
[5] THE INTERFERON-INDUCIBLE AUTOANTIGEN, IFI-16 - LOCALIZATION TO THE NUCLEOLUS AND IDENTIFICATION OF A DNA-BINDING DOMAIN
DAWSON, MJ
TRAPANI, JA
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1995, 214 (01) : 152 - 162
[6] Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma
DeYoung, KL
Ray, ME
Su, YA
Anzick, SL
Johnstone, RW
Trapani, JA
Meltzer, PS
Trent, JM
[J]. ONCOGENE, 1997, 15 (04) : 453 - 457
[7] Fischer D, 2000, Pac Symp Biocomput, P119
[8] Genes with homology to mammalian apoptosis regulators identified in zebrafish
Inohara, N
Nuñez, G
[J]. CELL DEATH AND DIFFERENTIATION, 2000, 7 (05) : 509 - 510
[9] The human interferon-inducible protein, IFI 16, is a repressor of transcription
Johnstone, RW
Kerry, JA
Trapani, JA
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (27) : 17172 - 17177
[10] GenTHREADER: An efficient and reliable protein fold recognition method for genomic sequences
Jones, DT
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1999, 287 (04) : 797 - 815

← 1 2 →